Yellow Fever Vaccine is recommended for travelers to areas where Yellow Fever is epidemic. This year (2015) the Advisory Committee on Immune Practices made new recommendations based on studies of the persistence of yellow fever vaccine. The vaccine produces long term immunity that obviates the necessity of a booster shot. The benefits of a booster shot are so slim, they are outweighed by low probability side effects. Good News. One shot and you are set for life.
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Source: Living With Insects Blog