Underside of Immature Bed Bug
A major challenge for blood feeding insects is preventing blood platelets from aggregating (clotting) and blocking the blood intake tube. Sequencing of the Bed Bug genome* gives clues about adaptations for blood feeding. The Bed Bug has an expanded suite of apyrases, salivary proteins that interfere with ADP-dependent platelet aggregation.
Feeding without triggering pain is an important trait to avoid detection. Bed Bugs have 12 members of the inositol…
Source: Living With Insects Blog